The room takes its name from Via Guantai Nuovi, one of the oldest streets in the historic center, which owes its name to the presence of artisans who made both refined gloves for the finest Neapolitan nobility and rough work gloves. The "Guantai" room is spread over two levels, with a height of 6.40 meters and a total floor area of 59.40 square meters, comfortably accommodating 6 people. The double level also allows for a good deal of privacy during the stay. The headboard of the master double bed is made from a 1920 glove chest salvaged from a former shop on Via Toledo that sold fine and elegant handcrafted gloves. The bedroom is equipped with a wardrobe, a glass coffee table, and armchairs.

The mezzanine level features a double bed that can be split into two single beds upon request.

The bedroom, in addition to being very spacious, also features an outdoor balcony with chairs and a table overlooking Via Paladino. The 4-meter-high windows flood the room with light throughout the day.

The bathroom is located on the first floor and does not have a bidet, but it does have a shower head connected to the toilet.